Package index • Medusa

All functions

Medusa Medusa-package: Medusa: Mendelian Estimation in Distributed Standardized Analytics
buildMRCohort(): Site-level cohort extraction from OMOP CDM
buildMRCovariates(): Covariate assembly using FeatureExtraction
complementAllele(): Get Complement of a DNA Allele
computeApproxFStatistic(): Compute Approximate F-statistic from GWAS Summary Statistics
computeMREstimate(): Wald ratio MR estimate from pooled profile likelihood
convertGenotypeString(): Convert VCF-Style Genotype Strings to Integer Allele Dosage
createDefaultMRCovariateSettings(): Default FeatureExtraction settings for Medusa
createInstrumentTable(): Build instrument table from user-provided data
exportSiteProfile(): Export a Site Profile to CSV
fitOutcomeModel(): Outcome model with exact grid likelihood evaluation
generateMRReport(): Self-contained HTML report for MR analysis
getMRInstruments(): Instrument assembly from OpenGWAS
harmonizeAlleles(): Allele harmonization for Mendelian Randomization
importSiteProfile(): Import a Site Profile from CSV
isStrandAmbiguous(): Check for Strand-Ambiguous SNPs
launchResultsExplorer(): Shiny dashboard for MR diagnostics and results
mrTheme(): Consistent plotting theme for Medusa package
plotLikelihoodProfile(): Likelihood profile visualization
plotSensitivityForest(): Forest plot comparing MR methods
poolLikelihoodProfiles(): Federated one-shot likelihood pooling
runInstrumentDiagnostics(): Instrument diagnostics for MR analysis
runNegativeControlAnalysis(): Empirical method validation using negative control outcomes
runSensitivityAnalyses(): Standard Mendelian Randomization sensitivity analyses
simulateCovariateData(): Simulate Covariate Data
simulateInstrumentTable(): Simulate an Instrument Table
simulateMRData(): Simulate MR Data with Known Causal Effect
simulateNegativeControlOutcomes(): Simulate Negative Control Outcome Columns
simulateSiteProfiles(): Simulate Site Profile Likelihood Objects
validateAgainstTwoSampleMR(): Single-site cross-check against standard summary-data MR